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In a sleepy Ohio town, two young girls find each other on line. Their friendship blossoms and then becomes something deeper. But when one of the girls hooks up with someone new, things take a dark turn and police have a murder to solve.

Michael Falco, Gary Evans, and Tim Rysedorph all come from working-class South Troy, NY. Friends since childhood, they dream of careers in music and the arts. But to survive in this Rust Belt town, they turn to small-time criminal activity.

A former deejay living in California, inherits money from his wealthy father. The heir's BFF, a banker, offers to help him manage the windfall, but the two have a falling out that ends up with a showdown, a murder and a manhunt.

Two West Virginia girls, best friends since third grade, turn on each other when a third girl transforms their solid duo into an unstable trio. When one of the girls goes missing, police focus in on her BFF and eventually prove that she's the killer.

Lula Young and Linda Leedom seem like typical moms. They live on a quiet suburban street, raising their families. Through sickness and heartbreak, Lula and Linda are best friends and perfect neighbors. To make her dreams come true, one will do anything.

Can we ever escape our past? An organic farmer, Patrick, meets a lumber mill worker, Gary, in Washington's Olympic Peninsula. They become close friends, and Patrick invites him to share his cabin in the woods. But one of them is hiding a dark secret.

A heavily pregnant woman is viciously attacked by a woman obsessed with making the unborn child her own. A couple cling to the rafters of their home as Hurricane Ike unleashes its fury on them.

A dream vacation turns into a murderous nightmare for an 11-year-old girl when she is orphaned and left to drown on a sinking yacht.

A convenience store worker plays dead to escape her abductor. An endurance athlete faces her greatest challenge ever after falling 60 feet in a remote canyon.

A missionary working in Haiti is ambushed, shot and held for ransom by a gang. A tunneler returns to an underground shaft minutes after escaping to rescue two colleagues from the flooded cavity.

Randy and Justin chase down a suspected car thief, while both EMT teams respond to emergency calls involving children in distress.

If every night in New Orleans is an adventure, this one is filled with characters in situations unlike any other.

On the tenth anniversary of Hurricane Katrina, everyone in New Orleans and on the Nightwatch recall their experiences with the storm, and reflect upon the significance it still holds in their lives.

Like any dad, Titus wants the best for his son. As an EMT, he sees just how dire life can get. From drug addicts desperate to kick their problems, to assault victims, to a teenager who drove his car into a tree.

The team celebrates the opening of its new headquarters, finally complete after 10 years of working out of trailers.

With Covid-19 raging across the city, the New Orleans EMS responders face an unfolding series of crises that include a vehicle rollover from a police pursuit, and a victim with close-range gunshot wounds.

Every call on the Nightwatch can go in one of two directions. And when the calls come from every direction.

Like the saying goes, "If you stay ready, you never have to get ready" and that is a code Tampa's first responders live by.

New Orleans first responders battle freezing temperatures as they treat a driver trapped after a serious car accident, a man hit by a streetcar, a delirious patient who doesn't want to part with his dog, and a woman with a surprisingly poignant backstory.

Officers Roni and Cooper find themselves in a breathless foot chase after people are stabbed at a nightclub.

On a hot, humid night in New Orleans, there's no escaping the temperatures as tempers rise and violence swells.

Working together for years has turned Titus and Dan into great friends. But on their shift, they inevitably come across folks who are the victims of crimes perpetuated by those closest to them.